Translational Nanomedicine

Part I Laboratory Techniques -- Chapter 1 Microfluidics In Nanomedicine -- 1 Introduction -- 1.1 Nanomedicine Development -- 1.2 Microfluidics Technology -- 2 Microfluidic Assembly Of Nanomedicines -- 3 Microfluidic Characterization Of Nanomedicines -- 4 Microfluidic Evaluation Of Nanomedicines -- 4.1 Mimicking Physiological Environments -- 4.2 Endothelial Cell Systems -- 4.3 Organ-on-a-chip -- 4.4 Renal Toxicity And Hepatotoxicity -- 4.5 Live Tissue Explants -- 5 Challenges And Opportunities -- 6 Concluding Remarks Acknowledgments -- References -- Chapter 2 Quantum Dots For Biomedical Delivery Applications -- 1 Introduction -- 2 Properties Of Qds -- 3 Lithographically Defined Qds -- 4 Colloidal Qds -- 5 Qds Application In Optics -- 6 Transport (electrical) Properties Of Qds -- 7 Application Of Qds In Diagnostics -- 8 Nucleic Acid Detection -- 9 Application Of Qds In Drug Treatments -- Acknowledgments -- References -- Part Ii Devices -- Chapter 3 Dna Origami Nanorobots -- 1 Introduction To Robotics -- 1.1 A Brief History Of Robotics -- 1.2 Robotic Control Of Molecules -- 2 Dna Nanotechnology -- 2.1 Computing 2.2 Nanofabrication -- 2.3 Nucleic Acid Enzymes -- 2.4 Nucleic Acid Sensors -- 2.5 Dna Actuators And Motors -- 2.6 Miscellaneous Functions Of Nucleic Acids -- 2.7 Dna Origami -- 2.8 Computer-aided Design (cad) Tools For Dna Nanostructures -- 2.9 Designing Scaffolded Origami In Cadnano: A Guided Tour -- 3 Dna Nanorobotics -- 3.1 Case Study: A Dna Nanorobot -- 3.2 Sensing The Environment -- 3.3 Information Processing And Logic Types -- 3.4 Collective Behaviors -- 3.5 Synthetic Genetic Circuits And Dna Nanorobotics -- 4 Challenges Of Applying Dna Nanorobots To Therapeutics 5 Summary And Conclusions -- References -- Chapter 4 Graphene And Graphene Derivatives In Biosensing, Imaging, Therapeutics, And Genetic Engineering -- 1 Introduction -- 2 Biosensing -- 2.1 Modification Of Bioreceptor On Graphene By Covalent And Noncovalent Interactions -- 2.2 Advantage Of Graphene/nanoparticle Hybrids In Enhancing Transducer Performance -- 3 Bioimaging -- 3.1 Optical Imaging: Nir Imaging, Fluorescence, Multiphoton Excitation Imaging -- 3.1.1 Nir Imaging -- 3.1.2 Fluorescence Imaging -- 3.1.3 Multiphoton Excitation Imaging -- 3.2 Localized Surface Plasmon Resonance (lspr) 3.3 Raman Imaging -- 3.4 Magnetic Resonance Imaging (mri) -- 3.5 Positron Emission Tomography (pet) -- 4 Therapeutics -- 4.1 Drug Loading By Noncovalent Interactions -- 4.2 Drug Loading By Host-guest Interaction -- 4.3 Controlled Release System -- 4.4 Photodynamic And Photothermal Therapy -- 4.5 Combination Of Diagnostics And Therapeutics: Graphene-based Theranostics System -- 5 Genetic Engineering -- 6 Conclusions -- Acknowledgments -- References -- Chapter 5 Synthetic Gene Circuits -- 1 Introduction To Synthetic Gene Circuits -- 2 Building Blocks Of Synthetic Gene Circuits Edited By Robert A. Meyers. 2.1 The Chassis: Choice Of The Host Cell Includes Bibliographical References And Index. Electronic Reproduction. Ipswich, Ma Available Via World Wide Web.