S-Adenosylmethionine-Dependent Methyltransferases: Structures and Functions

Called AdoMet by those who know it well, or spell it often, S-adenosyl-L-methionine is the second most commonly used enzyme cofactor after ATP, and the methyltranferases dependent on them act on a wide variety of target molecules, including DNA, RNA, proteins, polysaccharides, lipids, and a range of small molecules. The 13 studies here emphasize the well-conserved architecture of the enzymes and the implications of that for their evolutionary history. They detail the structures, enzyme kinetics, and biological roles of examples from a wide spectrum of plant, animal, bacterial, and archaeal cell types. There is no index. Annotation c. Book News, Inc., Portland, OR (booknews.com)