Biflavanoids. Chemical and Pharmacological Aspects

Product Description Biflavanoids are an important class of plant metabolites offering a range of activities, good availability and relatively low toxicity. Long thought to hold possible therapeutic potential, the recent surge in interest for natural product drug discovery has further highlighted the possibility of using them in the discovery of new drugs, and Biflavanoids: Chemical and Pharmacological Aspects provides a quick reference to the area in a focused manner, to support and encourage further research.Beginning with a focus on the structural features and occurrence of biflavanoids, Chapter 1 reviews key background information including notes on nomenclature and natural distribution. Chapter 2 then goes on to discuss methods for identification and isolation, with separation and purification using various chromatography methods reviewed, followed by identification via UV spectroscopy, NRM spectroscopy and mass spectrometry. Synthesis is the focus of Chapter 3, with a broad range of synthetic methods outlined, before the book concludes in Chapter 4 by describing the biochemical pharmacology of Biflavanoids and their anticancer, antimicrobial, antiviral, anti-inflammatory and analgesic activity.With its discussion of both the underlying chemistry and biological activity of Biflavanoids, Biflavanoids: Chemical and Pharmacological Aspects is a concise guide to this important class of compounds for all those working in the fields of medicinal chemistry and natural products drug discovery. Review A concise guide to the chemistry and biological potential of this important class of natural product-sourced compounds About the Author Dr. Lone is a researcher at the Indian Institute of Integrative Medicine, India. His work, which has appeared in a number of top journals, is predominantly based on the discovery of bioactive compounds from natural products for drug development using a broad range of both classical and novel techniques.Mohd Akbar Khuroo is Senior Associate Professor for the Department of Chemisty and Coordinator of the Department of Science and Technology at the University of Kashmir, India. He has 22 publications to his name across a number of top journals, with a particular focus on collaborations with US institutes (including the universities of Mississippi, Pittsburg and Texas-Pan American). He is also co-author of two books with Dr Lone due to publish/published respectively with Springer and Lambert Academic Publishing. His research interests include drug discovery from natural products, with particular focus on structure based drug design, synthesis and biological evaluation of the natural products with high therapeutic potential