Immunotherapy for Gastrointestinal Cancer

Immunotherapy for Gastrointestinal Cancer

Author
David Kerr, Rebecca Johnson (eds.)
Publisher
Springer International Publishing
Language
English
Edition
1
Year
2017
Page
VIII, 252
ISBN
978-3-319-43061-4,978-3-319-43063-8
File Type
pdf
File Size
4.6 MiB

This book is about the manipulation of the immune system as a therapeutic approach to gastrointestinal cancer and its clinical applications, exploring therapeutic approaches which might be taken under the broad banner of immunotherapy.
Starting by introducing concepts of modern immunology, the clinical applications of immunotherapy are then discussed. The reader will learn about the three broad classes of immune therapeutic agents: cell-based treatment; antibody therapy; cytokine application and the key effector cells and mechanisms which might cause tumour rejection. The reverse side of this equation, the genetic and molecular mechanisms which the tumour can use to escape immune control and regulation, is also discussed. Through reviewing the most up-to-date evidence, this volume provides an overview of the important scientific lessons learned from past failure of immunotherapeutics in the clinic and highlights more positive recent data, coupled to practical guidelines for clinical usage.

Written by a team of worldwide experts, this is an indispensable guide for medical oncologists, surgical oncologists, radiation therapists, pharmacists, oncology nurse specialists.

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