Antibiotic Drug Discovery: New Targets and Molecular Entities

Antibiotic Drug Discovery: New Targets and Molecular Entities

Author
Steven M Firestine, Troy Lister, David Thurston, David Rotella, Ernesto Abel-Santos, Lizbeth Hedstrom, Christian Melander, Stewart Fisher, Cezar Khursigara, Linos Lazarides, Sylvie Garneau-Tsodikova, Carl J Balibar
Publisher
Royal Society of Chemistry
Language
English
Edition
1
Year
2017
Page
286
ISBN
978-1-78262-424-0,1782624244,978-1-78262-987-0,978-1-78801-149-5
File Type
pdf
File Size
14.3 MiB

Recent years have seen a resurgence of antibiotic drug discovery. This book brings together the relevant information to assess the state-of-the-art. It identifies and elaborates the most recent and compelling strategies for antibiotic drug discovery with a primary focus on new targets, mechanisms and molecular entities. Addressing the need for continued investment in antibiotic drug development, the book provides a point of reference for the rapidly expanding infectious disease research community.
In addition to its attention on new targets, the book focusses on the medicinal chemistry and chemistry of the targets. Within this framework, chapters from leading researchers in academia and industry address findings in important areas such as biofilm production, narrow spectrum antibiotics and novel antibacterials from previously uncultured soil bacteria.
This book will be a useful resource for postgraduate students and researchers in medicinal chemistry wishing to understand the latest approaches to antibiotic drug discovery.

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