Current Topics in Cellular Regulation, Volume 1 presents the fundamental mechanisms involved in the regulation of diverse cellular activities, including the transfer of genetic information, intermediary metabolism, and cellular differentiation. This book discusses the advances in the general area of cellular regulation. Organized into 10 chapters, this volume begins with an overview of the molecular models that attempt to provide the correlation of the kinetic properties of the protein with its structural architecture. This text then examines several aspects of metabolism and of metabolic enzymes that appear to represent adaptations to the need to limit solute concentrations and conserve solvent capacity. Other chapters consider the factors that determine the overall rates of metabolic pathways. This book discusses as well the biosynthetic pathways leading to the branched-chain amino acids. The final chapter deals with the structure and mechanism of action of pyruvate carboxylase. This book is a valuable resource for biologists and biochemists.