Oxidative Stress in Heart Diseases

Oxidative Stress in Heart Diseases

Author
Sajal Chakraborti, Naranjan S Dhalla, Nirmal K Ganguly, Madhu Dikshit
Publisher
Springer Singapore
Language
English
Edition
1st ed. 2019
Year
2019
Page
XIII, 596
ISBN
978-981-13-8272-7,978-981-13-8273-4
File Type
pdf
File Size
12.1 MiB

This book bridges the gap between fundamental and translational research in the area of heart disease. It describes a multidisciplinary approach, and demonstrates biochemical mechanisms associated with dysregulation of redox signaling, which leads heart disease. Presenting recent studies on improved forms of ROS scavenging enzymes; specific inhibitors for different ROS generating enzymes; and oxidant induced signaling pathways and their antagonists that allow subtle modulation of redox signaling, it also discusses the spatial and temporal aspects of oxidative stress in the cardiovascular system, which are of vital importance in developing better strategies for treating heart disease. Each chapter offers researchers valuable insights into identifying targets for drug development for different types of heart disease.

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