Bioanalysis of pharmaceuticals: sample preparation, separation techniques, and mass spectrometry

Bioanalysis of pharmaceuticals: sample preparation, separation techniques, and mass spectrometry

Author
Hansen, Steen HonoréPedersen-Bjergaard, StigRasmussen, Knut EinarStig Pedersen-Bjergaard
Publisher
John Wiley & Sons, Incorporated
Language
English
Year
2015
ISBN
9781118716816,9781118716823,9781118716830,1118716833,9781118716847,1118716841,9781118716861,1118716868
File Type
epub
File Size
11.5 MiB

Product Description Bioanalysis of Pharmaceuticals: Sample Preparation, Separation Techniques and Mass Spectrometry is the first student textbook on the separation science and mass spectrometry of pharmaceuticals present in biological fluids with an educational presentation of the principles, concepts and applications. It discusses the chemical structures and properties of low- and high-molecular drug substances; the different types of biological samples and fluids that are used; how to prepare the samples by extraction, and how to perform the appropriate analytical measurements by chromatographic and mass spectrometric methods.Bioanalysis of Pharmaceuticals: Sample Preparation, Separation Techniques and Mass Spectrometry:Is an introductory student textbook discussing the different principles and concepts clearly and comprehensively, with many relevant and educational examplesFocuses on substances that are administered as human drugs, including low-molecular drug substances, peptides, and proteinsPresents both the basic principles that are regularly taught in universities, along with the practical use of bioanalysis as carried out by researchers in the pharmaceutical industry and in hospital laboratoriesIs aimed at undergraduate students, scientists, technicians and researchers in industry working in the areas of pharmaceutical analyses, biopharmaceutical analyses, biological and life sciencesThe book includes multiple examples to illustrate the theory and application, with many practical aspects including calculations, thus helping the student to learn how to convert the data recorded by instruments into the real concentration of the drug substances within the biological sample. Review "The strength of the present book is the presentation of important aspects of pharmaceutical bioanalysis within an educational frame with many examples accompanied by questions and answers that will guide undergraduate students in their self-study efforts." (Analytical and Bioanalytical Chemistry 2016) From the Inside Flap Bioanalysis of Pharmaceuticals: Sample Preparation, Separation Techniques and Mass Spectrometry is the first student textbook on the separation science and mass spectrometry of pharmaceuticals present in biological fluids with an educational presentation of the principles, concepts and applications. It discusses the chemical structures and properties of low- and high-molecular drug substances; the different types of biological samples and fluids that are used; how to prepare the samples by extraction, and how to perform the appropriate analytical measurements by chromatographic and mass spectrometric methods. Bioanalysis of Pharmaceuticals: Sample Preparation, Separation Techniques and Mass Spectrometry: • Is an introductory student textbook discussing the different principles and concepts clearly and comprehensively, with many relevant and educational examples • Focuses on substances that are administered as human drugs, including low-molecular drug substances, peptides, and proteins • Presents both the basic principles that are regularly taught in universities, along with the practical use of bioanalysis as carried out by researchers in the pharmaceutical industry and in hospital laboratories • Is aimed at undergraduate students, scientists, technicians and researchers in industry working in the areas of pharmaceutical analyses, biopharmaceutical analyses, biological and life sciences The book includes multiple examples to illustrate the theory and application, with many practical aspects including calculations, thus helping the student to learn how to convert the data recorded by instruments into the real concentration of the drug substances within the biological sample. From the Back Cover Bioanalysis of Pharmaceuticals: Sample Preparation, Separation Techniques and Mass Spectrometry is the first student textbook on the separation science and mass spectrometry of pharmaceuticals present

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