The Art, Science and Technology of Pharmaceutical Compounding

Compounding has always been part of pharmacy practice. Today, the need for compounding is growing, with the prevalence of drug shortages, outsourcing of compounding services by hospitals, and patients’ need for individualized preparations. Compounding pharmacies now have the opportunity to obtain accreditation. The Art, Science, and Technology of Pharmaceutical Compounding presents in a logical and progressive format all the information that pharmacists and student pharmacists need to understand the purpose and processes of compounding. Author Loyd V. Allen Jr., the preeminent expert, covers basic guidelines, economic and technical factors that compounding pharmacists must consider, and all aspects of good manufacturing practices for compounded medications. In this fifth edition, all chapters have been updated and several significantly revised—particularly “Compounding with Hazardous Drugs”—and three new chapters have been added: “Pharmaceutical Compounding Errors,” “Foams,” and “Compounding with Special Ingredients.” Information on the new law affecting compounding, the Drug Quality and Security Act, is incorporated throughout the book. Chapter 13 now includes information on compounding "films."

KEY FEATURES: The initial chapters describe the requisite facilities and equipment, record keeping, calculations, and quality control. Three new chapters: “Pharmaceutical Compounding Errors,” “Foams,” and “Compounding with Special Ingredients.” Fifteen chapters are devoted to the compounding of each dosage form in turn, from powders and granules to injectables. Additional chapters cover veterinary compounding, compounding for special populations, compounding for specific procedures, compounding for clinical studies, compounding cosmetics, compounding with hazardous drugs, and compounding in the event of a natural disaster or terrorist attack. Nine appendices provide essential information on the compounding process and examples of standard operating procedures. The necessary ingredients and steps are listed for compounding more than 200 sample formulations, including bases, vehicles, and ingredient-specific preparations. Updated throughout, including information on the new Drug Quality and Security Act.